ea0077p188 | Metabolism, Obesity and Diabetes | SFEBES2021
Haq Naila
, Toczyska Klaudia
, Olaniru Oladapo
, Atanes Patricio
, Beck-Sickinger Annette
, Bewick Gavin
Type 1 diabetes (T1D) is an autoimmune, heterogenous disease caused by immune-mediated destruction of insulin-producing β-cells in the pancreas. The only approved treatment strategies are exogenous insulin replacement therapy and islet transplantation. Leading experimental approaches have focussed on suppression and/or modulation of the immune system. However, efforts to increase β-cell survival are also of great interest. Recent studies in our lab have identified ne...